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Vision Loss - RVO!

Updated: Mar 26

Retina blockage –Pathway blocked Into and out. Thus swelling and thus blurriness. Retinal vein occlusion (RVO) is a blockage in a small blood vessel that carries blood to and away from your retina.

Symptoms include blurry vision or vision loss in one eye, which may develop suddenly.

RVO can lead to serious complications like swelling or bleeding in your eye, it is not always evident, the unseen damage is inside, imagine an air tube with a blowout on the side wall, this is very similar in appearance, but MJCH smaller, but still deadly..

There's no cure for CRVO, but treatment can improve your vision or keep your symptoms from getting worse. Catching CRVO early and getting treatment as soon as possible can help lower the chance of vision loss.

Treatments include injections of medicines called anti-VEGF drugs which can reduce VEGF levels in your eye — which helps reduce and prevent macular edema. Some people only need 1 injection, but it’s common to need more. Steroid medicines can also help with swelling.

CRVO occurs when the central vein that carries blood away from the retina, the light-sensitive tissue in the back of the eye, becomes blocked. When blood flow is disrupted, adequate levels of oxygen fail to reach the retina, triggering the release of vascular endothelial growth factor (VEGF). VEGF increases the permeability of blood vessels, leading to swelling in the central part of the retina—a condition known as macular edema, the leading cause of vision loss from CRVO.

Central Retinal Vein Occlusion .

Monthly eye injections of Avastin (bevacizumab) are as effective as the more expensive drug Eylea (aflibercept) for the treatment of central retinal vein occlusion (CRVO), according to a clinical trial funded by the National Eye Institute (NEI), part of the National Institutes of Health. After six monthly injections, treatment with either drug improved visual acuity on average from 20/100 to 20/40.


Eylea is an anti-VEGF drug approved by the Food and Drug Administration for treatment of CRVO-associated macular edema. Avastin is a less expensive anti-VEGF drug ($60 per dose, versus $1850 per dose for Eylea). Avastin is an FDA approved biologic for treating cancer, but is frequently used off-label to treat conditions of the eye, including CRVO. Anti-VEGF drugs make the injured blood vessels less leaky, thereby decreasing macular edema

Without treatment, these issues can lead to vision loss.

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